Thermo Fisher Scientific CACNA1I Polyclonal Antibody
CACNA1I 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 사용 가능. 인간 시료 반응성. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관. 신경세포 칼슘 신호 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 450–500 of human CACNA1I (CaV3.3) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CACNA1I.
Target Information
CaV3.3 encodes the pore-forming alpha subunit of a voltage-gated calcium channel. It belongs to the T-type, low voltage-activated calcium channels, characterized by slower activation and inactivation compared to other T-type channels.
CaV3.3 is implicated in neuronal calcium signaling, and alternative splicing produces multiple transcript variants. Voltage-gated calcium channels (CaV) mediate calcium influx in response to depolarization and regulate intracellular processes such as contraction, secretion, neurotransmission, and gene expression.
Diseases associated with CACNA1I include Childhood Absence Epilepsy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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