Thermo Fisher Scientific BAK1 Polyclonal Antibody
인간 BAK1 단백질의 아미노산 1-50 서열에 대응하는 합성 펩타이드로부터 제작된 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 미토콘드리아에서 세포자멸사 관련 연구에 활용 가능. 액상 형태로 제공되며 -20°C에서 보관.
- 카탈로그번호
- PA5109442
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 1–50 of human BAK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854853 |
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities.
This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and release of cytochrome c.
Additionally, it interacts with the tumor suppressor P53 after exposure to cell stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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