Thermo Fisher Scientific BAMBI Polyclonal Antibody
Thermo Fisher Scientific의 BAMBI Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 BAMBI 단백질을 검출하기 위한 고품질 항체입니다. Western blot 및 ELISA에 최적화되어 있으며, 고순도 친화 크로마토그래피로 정제되었습니다. 안정적인 PBS/glycerol 버퍼로 장기 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–152 of human BAMBI (NP_036474.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854854 |
Product Specific Information
Immunogen Sequence:
VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN SNSPLTHGCL DSLASTTDIC QAKQARNHSG TTIPTLECCH EDMCNYRGLH DVLSPPRGEA SGQGNRYQHD GSRNLITKVQ ELTSSKELWF RA
Target Information
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane-spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development.
BAMBI transcription is regulated by beta-catenin, BMP, smad3, and smad4.
Expression increases in colorectal and hepatocellular carcinomas compared to non-cancerous tissues.
It is highly expressed during odontogenesis and coexpressed with Bmp-4 during early Xenopus embryogenesis.
Detected in poorly metastatic human melanoma cell lines.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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