Thermo Fisher Scientific BAZ2A Polyclonal Antibody
Thermo Fisher Scientific의 BAZ2A Polyclonal Antibody는 Human 및 Mouse 시료에 반응하는 Rabbit IgG 항체로, Western blot과 ELISA에 적합합니다. Affinity Chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5109445
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 97–295 of human BAZ2A (TIP5) (NP_0384772) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854856 |
Product Specific Information
Immunogen sequence:
QYPSANPGSN LKDPPLLSQF SGGQYPLNGI LGGSRQPSSP SHNTNLRAGS QEFWANGTQS PMGLNFDSQE LYDSFPDQNF EVMPNGPPSF FTSPQTSPML GSSIQTFAPS QEVGSGIHPD EAAEKEMTSV VAENGTGLVG SLELEEEQPE LKMCGYNGSV PSVESLHQEV SVLVPDPTVS CLDDPSHLPD QLEDTPILS
Target Information
TIP5 is the large subunit of the nucleolar remodeling complex NoRC, which represses ribosomal gene transcription. Histone deacetylation is involved in this repression, and TIP5 associates with histone deacetylase HDAC1 to mediate histone deacetylation near the rDNA promoter. The interaction between TIP5 and HDAC1, essential for transcriptional repression, is established via the C-terminal PHD finger and bromodomain.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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