Thermo Fisher Scientific IGF1R alpha Monoclonal Antibody (1H7), PE
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA516465 | - | Thermo Fisher Scientific MA516465 IGF1R alpha Monoclonal Antibody (1H7), PE 100 tests pk | 재고문의 | pk | 631,000원 | - | 694,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
Neat
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
1H7
Immunogen
purified human placental IGF-I receptor if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
IGF1R (CD221),
uniProtId:
P08069-1,
ncbiNodeId:
9606,
antigenRange:
1-1367,
antigenLength:
1367,
antigenImageFileName:
MA5-16465_IGF1R_CD221_P08069-1_House_mouse.svg,
antigenImageFileNamePDP:
MA5-16465_IGF1R_CD221_P08069-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
PE PE PE
View additional formats
Excitation/Emission Max
565/576 nm View spectra
Form
Lyophilized
Concentration
Conc. Not Determined
Purification
Protein A
Storage buffer
PBS with 1% BSA, 5% sucrose
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2537979
Product Specific Information
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Target Information
IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers. The protein is a tetramer consisting of two alpha, and two beta subunits. The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2. Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136. The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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