Thermo Fisher Scientific HEXA Monoclonal Antibody (714729)
Human HEXA 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 단백질 A/G로 정제된 동결건조 형태이며, PBS와 trehalose로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 714729 |
| Immunogen | Sf21-derived recombinant human Hexosaminidase A (HEXA) Met1–Thr529 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609677 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase, which, together with the cofactor GM2 activator protein, catalyzes the degradation of ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Beta-hexosaminidase consists of two subunits (alpha and beta), encoded by separate genes and belonging to family 20 of glycosyl hydrolases.
Mutations in these genes lead to accumulation of GM2 ganglioside in neurons, causing GM2 gangliosidoses such as Tay-Sachs disease (GM2-gangliosidosis type I).
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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