Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI2B12), TrueMAB
PDGFRA 단백질을 인식하는 Mouse monoclonal antibody로 Western Blot에 최적화됨. Human 시료에 반응하며, 동결건조 형태로 제공. PBS buffer(pH 7.3, 8% trehalose) 기반, 보존제 미함유. -20°C 보관, 반복 동결·해동 피할 것.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–324 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PDGFRA (Platelet-Derived Growth Factor Receptor Alpha) is a cell surface receptor tyrosine kinase that binds platelet-derived growth factor family members, which act as mitogens for mesenchymal-origin cells.
The bound growth factor determines receptor composition as homodimer or heterodimer (α/β).
Knockout mouse studies show PDGFRA is critical for kidney development; heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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