Thermo Fisher Scientific Human AFP Synthetic Peptide
인간 AFP의 중심부 14개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-21004 항체의 블로킹 펩타이드로 사용 가능. 인간 반응성, 액상 형태, PBS 버퍼 내 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP1118
- 판매단위
- pk
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the center of human AFP.
PEP-1118 can be used as a blocking peptide with polyclonal antibody PA5-21004.
Target Information
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also occur in individuals with no obvious pathology.
The protein is considered the fetal counterpart of serum albumin, and AFP and albumin genes are located in tandem on chromosome 4 in the same transcriptional orientation. AFP exists in monomeric, dimeric, and trimeric forms and can bind copper ions, nickel ions, fatty acids, and bilirubin.
AFP levels in amniotic fluid are used to screen for spina bifida and anencephaly. Elevated serum AFP has been identified in patients with hepatocellular carcinoma (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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