Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser217, Ser221) Recombinant Rabbit Monoclonal Antibody (MEK12S217S221-H2), PE
인간 MEK1/MEK2 Ser217/221 인산화 부위를 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. PE 형광 표지로 유세포분석에 적합. HEK293 발현 시스템, Protein A/G 정제, 4°C 보관.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEK12S217S221-H2 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser217/221 of human phospho MEK1/2 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897031 |
Additional Formats
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In the brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual specificity kinase phosphorylating both threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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