Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI2H6), TrueMAB
MMP3 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer(8% trehalose) 내 보관, -20°C에서 안정적. 연구용으로 조직 재형성 및 MMP3 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form and activated by extracellular proteinase cleavage.
MMP3 binds zinc and calcium ions and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin.
It plays roles in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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