Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI2D6), TrueMAB
Human MMP3 단백질(aa 246-477)을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합합니다. Lyophilized 형태이며, PBS buffer(8% trehalose)에 보존됩니다. 연구용으로 조직 재생 및 단백질 분해 관련 연구에 활용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246-477 of human MMP3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted as a pro-protein and activated by extracellular proteinase cleavage.
MMP3 binds zinc and calcium ions and exhibits metallo-endopeptidase activity.
The active enzyme degrades collagen, gelatin, fibronectin, and laminin, contributing to wound repair and tissue remodeling.
Mutations in the gene are associated with coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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