Thermo Fisher Scientific CD19 Monoclonal Antibody (LT19)
CD19 단백질을 인식하는 LT19 클론의 mouse monoclonal 항체로, 인간 B 세포 표면의 CD19 항원을 검출합니다. Flow cytometry 및 immunoprecipitation에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 제품입니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 5 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LT19 |
| Immunogen | B lymphoblast cell line Daudi |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071410 |
Available Conjugated Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells. Expression is lost on plasma cells.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on nearly all peripheral B cells and certain myeloid leukemia cells. CD19 functions as a coreceptor with the B cell receptor (BCR), lowering the threshold for antigen receptor-dependent stimulation. It plays a central role in regulating normal and malignant B cell proliferation and differentiation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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