Thermo Fisher Scientific CD41 Monoclonal Antibody (MEM-06)
CD41 단백질을 인식하는 마우스 모노클론 항체로 인간 시료에 반응. Flow Cytometry에 적합하며 1–5 µg/mL 농도에서 사용 가능. 액상 형태, Protein A 정제, 4°C 보관. 혈소판 및 거핵세포 표지 연구에 유용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-06 |
| Immunogen | Leukocytes from a patient suffering from a LGL type leukemia |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075445 |
Additional Formats
- Alexa Fluor 488 (MA5-18137)
- Alexa Fluor 700 (MA5-28562)
- APC (MA1-19779)
- Biotin (MA1-19518)
- FITC (MA1-19596)
- PE (MA1-19648)
- PerCP (MA5-28563)
- Request custom conjugation
Product Specific Information
This antibody reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains: GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits—120 kDa alpha and 23 kDa beta—that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to proteins such as von Willebrand factor, fibrinogen, fibronectin, and vitronectin. It is mainly expressed on the megakaryocyte–platelet lineage and is associated with diseases such as Glanzmann Thrombasthenia and Platelet type-16 bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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