Thermo Fisher Scientific Phospho-EZH2 (Thr367) Polyclonal Antibody
EZH2 단백질의 Thr367 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot에 적합하며, 인간, 마우스, 랫트 시료에서 반응. 고순도 정제, PBS/glycerol buffer에 보존, 연구용 전용.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:3,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EZH2 (Accession Q15910), corresponding to amino acid residues around phosphorylated Thr367 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817623 |
Product Specific Information
Antibody detects endogenous levels of EZH2 only when phosphorylated at T367.
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG proteins form multimeric complexes that maintain transcriptional repression across cell generations. EZH2 associates with embryonic ectoderm development protein, VAV1 oncoprotein, and X-linked nuclear protein. It may play roles in hematopoietic and central nervous system development. Mutations in EZH2 are linked to Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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