Thermo Fisher Scientific MICA/B Monoclonal Antibody (6D4), PE-Cyanine7
인간 MICA/B 단백질을 인식하는 단클론 항체로, PE-Cyanine7 형광으로 표지되어 있습니다. NK 및 T세포 활성화 연구에 적합하며, 유세포분석(Flow Cytometry)에 사용됩니다. 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D4 |
| Immunogen | Transfected C1R cells expressing MICA |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898640 |
Additional Formats
- Alexa Fluor 647 (MA5-38723)
- Alexa Fluor 700 (MA5-38724)
- APC (MA5-38725)
- Biotin (MA5-38726)
- FITC (MA5-38727)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes a common extracellular epitope on MICA and MICB glycoproteins, which are transmembrane ligands of CD314 (NKG2D). It can block CD314-mediated activation of NK cells and cytotoxic T cells.
Target Information
MICA encodes a highly polymorphic MHC (HLA) class I chain-related gene A. The protein is expressed on the cell surface but does not associate with beta-2-microglobulin like canonical class I molecules. MICA functions as a stress-induced antigen broadly recognized by intestinal epithelial gamma delta T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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