Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), Alexa Fluor 647
인간 CD45 항원을 인식하는 단클론 항체로, Alexa Fluor 647 형광 표지로 유세포분석에 적합. 모든 인간 혈액세포에서 발현되는 CD45 단백질 검출에 사용. 고순도 크로마토그래피로 정제되어 안정적이며, 4°C 암소 보관 권장.
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Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), Alexa Fluor 647
Applications
- Flow Cytometry (Flow)
Tested Dilution: 4 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | Human peripheral blood mononuclear cells |
| Conjugate | Alexa Fluor™ 647 |
| Excitation / Emission Max | 650 / 671 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898642 |
Additional Formats
- Alexa Fluor 488
- APC-Cyanine7
- PE-Cyanine5
- PerCP
- Custom conjugation available
Product Specific Information
This antibody reacts with an extracellular epitope of all alternative forms of human CD45 antigen (Leukocyte Common Antigen), a 180–220 kDa single-chain type I transmembrane protein expressed at high levels on all cells of hematopoietic origin, except erythrocytes and platelets.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed on all nucleated hematopoietic cells. It comprises approximately 10% of surface proteins in lymphocytes and is absent on non-hematopoietic cells. CD45 plays a key role in lymphocyte development and antigen signaling by regulating Src-family kinases and JAK kinases. It also influences integrin-mediated signal transduction, apoptosis, and various immunological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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