
Thermo Fisher Scientific PRDX3 Polyclonal Antibody
PRDX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 미토콘드리아 내 위치 검출에 적합하며, 고농도 액상 형태로 제공. 연구용으로만 사용 가능.
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- PA591918
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide of human PRDX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.29 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806326 |
Product Specific Information
Positive Samples: SW620, K-562, ES-2, U-937, HepG2, HT-29, Raji, Mouse liver, Mouse kidney
Cellular Location: Mitochondrion
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are associated with cell proliferation, differentiation, and apoptosis. Approximately 50 isoforms exist, classified by amino acid sequence homology and active site cysteine residues, exhibiting thiol-specific antioxidant activity across all kingdoms.
Mammalian Prx includes six members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx types. Except for Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes possess thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system.
Mammalian Prxs are 20–30 kDa in molecular size and vary in subcellular localization:
- Prx I, II, VI: Cytosol
- Prx III: Mitochondria
- Prx IV: Endoplasmic Reticulum and secretion
- Prx V: Peroxisome, mitochondria, and cytosol
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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