Thermo Fisher Scientific PDX1 Polyclonal Antibody
PDX1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 마우스 시료에 반응. 액상 형태로 제공되며, -20°C에서 보관. 췌장 발달 및 인슐린 유전자 발현 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human PDX1 (P52945) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.44 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806324 |
Product Specific Information
- Positive Samples: Mouse intestine
- Cellular Location: Cytoplasm, Nucleus, Cytosol
- Immunogen sequence:
MNGEEQYYAA TQLYKDPCAF QRGPAPEFSA SPPACLYMGR QPPPPPPHPF PGALGALEQG SPPDISPYEV PPLADDPAVA HLHHHLPAQL ALPHPPAGPF
Target Information
The protein encoded by this gene acts as a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It plays a major role in pancreas development and glucose-dependent regulation of insulin gene expression. Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity-onset diabetes of the young type 4 (MODY4).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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