Thermo Fisher Scientific CD93 (AA4.1) Monoclonal Antibody (AA4.1), eFluor 450, eBioscience
마우스 CD93(C1qRp) 인식 단클론 항체로, eFluor 450 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. B세포 발달 및 조혈 전구세포 연구에 활용되며, 405/445 nm에서 여기 및 방출됩니다. 4℃ 보관, 동결 금지.
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1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD93 (AA4.1) Monoclonal Antibody (AA4.1), eFluor 450, eBioscience
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 0.5 µg/test
- Publications: View 6 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b, kappa |
| Recommended Isotype Control | Rat IgG2b kappa Isotype Control (eB149/10H5), eFluor™ 450, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AA4.1 |
| Conjugate | eFluor™ 450 |
| Excitation/Emission Max | 405/445 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2574084 |
Available Formats
- APC
- Biotin
- FITC
- PE
- PE-Cyanine7
- PerCP-Cyanine5.5
- Super Bright 436
- Super Bright 600
- Super Bright 702
- Request custom conjugation
Product Specific Information
The AA4.1 monoclonal antibody reacts with mouse C1qRp, an approximately 130–140 kDa C-type lectin-like type I transmembrane protein. This antigen is expressed on early stages of B cell development in bone marrow, and also detectable in adult spleen and fetal liver.
In combination with markers such as Thy-1, Sca-1, c-Kit, CD43, and CD24, it helps distinguish primitive and differentiated subsets of Lymphoid-Committed Progenitors (CLP).
Surface expression of IgM, CD23, and AA4.1 defines three transitional B cell subsets:
- T1: AA4.1⁺ / CD23⁻ / sIgM^hi
- T2: AA4.1⁺ / CD23⁺ / sIgM^hi
- T3: AA4.1⁺ / CD23⁺ / sIgM^lo
AA4.1 is also found in endothelial cells, megakaryoblasts, and platelets. Antibodies AA4.1 and 493 recognize different epitopes of the same molecule.
Applications Reported: Flow cytometric analysis
Applications Tested: Flow cytometric analysis of mouse bone marrow cells (≤0.5 µg/test).
Recommended to titrate antibody for optimal performance.
Fluorophore Information:
eFluor® 450 is an alternative to Pacific Blue®, excited at 405 nm and emitting at 445 nm. Ensure instrument compatibility.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
The encoded protein is a cell-surface glycoprotein and type I membrane protein originally identified as a myeloid cell-specific marker. It is believed to be involved in intercellular adhesion and apoptotic cell clearance. The cytoplasmic tail interacts with moesin, linking to the cytoskeleton and participating in cytoskeletal remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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