Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody
Thermo Fisher Scientific의 alpha Galactosidase Polyclonal Antibody는 인간 GLA 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 ELISA에 적합합니다. 고순도 친화성 정제 제품으로, 액상 형태이며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Positive Samples: HeLa
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 150–429 of human Galactosidase alpha (GLA) (NP_0001601) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901202 |
Product Specific Information
Positive Samples: HeLa
Immunogen sequence:
GYYDIDAQTF ADWGVDLLKF DGCYCDSLEN LADGYKHMSL ALNRTGRSIV YSCEWPLYMW PFQKPNYTEI RQYCNHWRNF ADIDDSWKSI KSILDWTSFN QERIVDVAGP GGWNDPDMLV IGNFGLSWNQ QVTQMALWAI MAAPLFMSND LRHISPQAKA LLQDKDVIAI NQDPLGKQGY QLRQGDNFEV WERPLSGLAW AVAMINRQEI GGPRSYTIAV ASLGKGVACN PACFITQLLP VKRKLGFYEW TSRLRSHINP TGTVLLQLEN TMQMSLKDLL
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins.
It predominantly hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose.
Mutations in this gene cause Fabry disease, a lysosomal storage disorder resulting from failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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