Thermo Fisher Scientific H4K12ac Polyclonal Antibody
H4K12ac Polyclonal Antibody는 인간, 생쥐, 랫트 시료에서 히스톤 H4 K12 아세틸화 검출에 사용됩니다. Western blot, IHC, ICC/IF, ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5116574
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic acetylated peptide around K12 of human Histone H4 (NP_0010292491) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901205 |
Product Specific Information
- Positive Samples: C2C12, C6
- Immunogen Sequence: GLGKG
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure in eukaryotic chromosomal fibers. Two molecules each of H2A, H2B, H3, and H4 form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction. The histone H4 gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails but contain a palindromic termination element and are located in the large histone gene cluster on chromosome 6.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-116574_H4K12ac_P62805-1_Rabbit.svg, PA5-116574_H4K12ac_P62805-1_Rabbit_PDP.jpeg)
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