Thermo Fisher Scientific Phospho-TK1 (Ser13) Polyclonal Antibody
Phospho-TK1 (Ser13) 특이적 폴리클로날 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 세포 분열 관련 TK1 인산화 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TK1 (Accession P04183), corresponding to amino acid residues around phosphorylated Ser13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816210 |
Product Specific Information
This antibody detects endogenous levels of Thymidine Kinase 1 (TK1) only when phosphorylated at Serine 13.
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP,
and is involved in DNA synthesis. TK1 is essential for the activity of several antiviral drugs (e.g., AZT) and is used for hybridoma selection in monoclonal antibody production. Its expression correlates with cell division, making it a valuable marker in proliferative studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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