Thermo Fisher Scientific Caspase 6 Recombinant Rabbit Monoclonal Antibody (SC56-09)
Caspase 6 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단일클론 항체로 높은 특이성과 민감도를 제공합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 안정적인 단백질 A 정제 및 장기 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC56-09 |
| Immunogen | Synthetic peptide within Human Caspase 6 (aa 210–249) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809488 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are classified as:
- Initiator caspases (activated by receptor clustering, e.g., Caspase-8, Caspase-9)
- Effector caspases (activated by mitochondrial permeability transition, e.g., Caspase-3, Caspase-7)
Activated initiator caspases process effector caspases, leading to cell collapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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