Thermo Fisher Scientific BAP31 Monoclonal Antibody (CC-1)
BAP31 단백질을 인식하는 Rat IgG2a 단클론 항체(CC-1). Western blot, IHC, ICC/IF, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 비인간 영장류 등 여러 종에서 반응. -20°C 보관, sodium azide 함유.
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- MA3002
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- pk
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Thermo Fisher Scientific BAP31 Monoclonal Antibody (CC-1)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,500–1:6,000 | View 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:10,000 | — |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | View 8 publications |
| ELISA | Assay-dependent | — |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Non-human primate |
| Published Species | Human, Mouse, Non-human primate |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CC-1 |
| Immunogen | Amino acid residues 230–246 of BAP31 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_325095 |
Product Specific Information
MA3-002 detects BAP31 from human, non-human primate, bovine, mouse, and hamster samples.
It has been successfully used in Western blot, ELISA, immunoprecipitation, immunofluorescent, and immunohistochemical procedures.
By Western blot, this antibody detects a 28-kDa protein corresponding to human BAP31.
The MA3-002 antigen is solubilized protein from human neuroendocrine cell line IMR-32 corresponding to the C-terminal region residues 230–246 of BAP31 protein.
This sequence is conserved in non-human primate, bovine, and hamster species.
Target Information
BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane-spanning protein of the endoplasmic reticulum.
It forms homo- and hetero-oligomers with BAP29 and acts as a potential apoptotic regulator associated with BCL-2/BCL-XL.
The C-terminal domain contains recognition sites for initiator Caspases 1 and 8, suggesting a role in programmed cell death.
BAP31 is involved in the transport of selected proteins to the Golgi apparatus and regulates CFTR expression.
Alteration of BAP31 function may influence chloride channel regulation in cystic fibrosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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