Thermo Fisher Scientific CDK7 Monoclonal Antibody (31TF2-1F8)
CDK7 단백질 검출용 Thermo Fisher Scientific의 단클론 항체. Western blot 및 면역세포염색에 적합. 인간 및 마우스 반응성. 비결합형 액상 형태로 제공되며, -20°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 24 publications |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Fish, Human, Non-human primate, Pig, Yeast |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 31TF2-1F8 |
| Immunogen | Synthetic peptide MALDVKSRAKRYEKLDFLGEGQ corresponding to aa 1–22 of human CDK7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608624 |
Product Specific Information
MA3-001 has been used successfully in Western blotting to detect Cyclin dependent kinase 7 in human lysates.
Target Information
The trimeric complex of CDK7, cyclin H, and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex links transcription regulation and the cell cycle. The bound complex contributes to BRCA1 double-strand break repair. CDK7 may be a target of germline cancer-inducing mutations.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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