Thermo Fisher Scientific Cytokeratin 6B (KRT6B) (Basal Cell Marker) Monoclonal Antibody (KRT6B/2116)
KRT6B 단백질을 인식하는 Monoclonal Antibody로, Human 및 Mouse 시료에 반응합니다. IHC (Paraffin) 및 IHC (PFA fixed) 실험에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. PBS buffer에 보존되며, 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT6B/2116 |
| Immunogen | Recombinant full-length human KRT6B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the keratin gene family. Type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Up to six type II cytokeratin (KRT6) genes have been identified, resulting from successive gene duplication events. These genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and glandular epithelia. Mutations in these genes are associated with pachyonychia congenita. Type II cytokeratins are clustered in a region of chromosome 12q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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