Thermo Fisher Scientific Astrin/MAP126 Polyclonal Antibody
Astrin/MAP126 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제됨. 액상 형태, 4°C 보관, 연구용 전용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 875 and 925 of human astrin (mitotic spindle associated protein p126) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon, and thymus.
SPAG5 localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase. It is essential for proper spindle formation and plays a role in sister chromatid cohesion and separation, regulating chromosome integrity.
SPAG5 forms a homodimer with a long stalk and globular head domain, creating aster-like structures. Upon DNA damage, it may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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