Thermo Fisher Scientific SIRP gamma Monoclonal Antibody (OX-119), FITC
인간 SIRP gamma(CD172g)를 인식하는 단클론성 항체로, FITC 형광 표지되어 유세포분석(Flow Cytometry)에 적합. 마우스 IgG1 아이소타입이며 Protein A로 정제됨. T 세포와 일부 B 세포에서 발현되는 SIRP gamma 검출에 사용.
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Thermo Fisher Scientific SIRP gamma Monoclonal Antibody (OX-119), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat-1:10
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-119 |
| Immunogen | Purified recombinant SIRPgammaCD4 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745185 |
Additional Formats
Product Specific Information
Mouse anti-Human CD172g antibody, clone OX119 recognizes human SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.
Target Information
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein belonging to the immunoglobulin gene superfamily.
SIRP gamma is expressed on most T lymphocytes and a subset of B-cells, but absent on myeloid cells.
CD172g has a truncated cytoplasmic tail similar to SIRP beta, but unlike SIRP beta, CD172g does not require DAP12 for surface expression.
Like SIRP alpha, CD172g binds to CD47 inducing apoptosis and is involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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