Thermo Fisher Scientific AMPK alpha-1 Monoclonal Antibody (C.458.5)
Rabbit monoclonal antibody specific for AMPK alpha-1 (C.458.5), suitable for Western blot applications. Reacts with human, mouse, rat, and non-human primate samples. Purified by affinity chromatography and supplied as liquid form for research use only.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.458.5 |
| Immunogen | Synthetic peptide corresponding to the amino-terminal sequence of human AMPKα |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982129 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, typically the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating:
- Cellular metabolism
- Transcription
- Cell cycle progression
- Cytoskeletal rearrangement and cell movement
- Apoptosis and differentiation
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. It is classified into 8 major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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