Thermo Fisher Scientific ENO1 Recombinant Rabbit Monoclonal Antibody (ARC0599)
Thermo Fisher Scientific의 ENO1 Recombinant Rabbit Monoclonal Antibody (ARC0599)은 인간, 마우스, 랫트에 반응하며 Western Blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 단일클론 항체로, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:6,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0599 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human ENO1 (P06733) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849016 |
Product Specific Information
Immunogen sequence:
MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT
Target Information
Enolase (2-phosphoglycerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate. It comprises three distinct subunits: alpha, beta, and gamma.
Non-neuronal Enolase (ENO1) is an isoform composed of two alpha subunits. The ENO1 gene also encodes a shorter monomeric structural lens protein, tau-crystallin.
This multifunctional enzyme plays roles in growth control, hypoxia tolerance, and allergic responses. It may function in the fibrinolytic system as a receptor and activator of plasminogen on the cell surface.
ENO1 is used as a diagnostic marker for various tumors and as a marker for hypoxic brain injury and endometriosis. Antibodies against ENO1 are found in sera from patients with cancer-associated retinopathy syndrome (CAR) and are identified as autoantigens in Hashimoto encephalopathy (HE), associated with Hashimoto thyroiditis (HT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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