Thermo Fisher Scientific delta Catenin Recombinant Rabbit Monoclonal Antibody (ARC0586)
Thermo Fisher Scientific의 delta Catenin Recombinant Rabbit Monoclonal Antibody (ARC0586)은 인간, 마우스, 랫트에 반응하며 Western blot, IHC, ELISA, IP 등에 적합합니다. HEK293 발현 시스템에서 제조된 고순도 항체로, PBS 버퍼에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0586 |
| Immunogen | Synthetic peptide corresponding to amino acids 869–968 of human δ-Catenin/p120 Catenin (O60716) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849009 |
Product Specific Information
Immunogen sequence:
TLPLIDRNQK SDKKPDREEI QMSNMGSNTK SLDNNYSTPN ERGDHNRTLD RSGDLGDMEP LKGTTPLMQD EGQESLEEEL DVLVLDDEGG QVSYPSMQKI
Target Information
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1, and ERBB2 receptors.
The association of catenins to cadherins forms a complex linked to the actin filament network, which is essential for cadherin-mediated cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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