Thermo Fisher Scientific MEF2D Monoclonal Antibody (OTI1E11), TrueMAB
MEF2D 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 시료 반응성이 있으며, 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–282 of human MEF2D produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MEF2D gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors.
These factors regulate muscle and neuronal cell differentiation and development, and are modulated by class II histone deacetylases.
Fusions with DAZAP1 due to chromosomal translocation have been identified in acute lymphoblastic leukemia, suggesting a role in leukemogenesis.
MEF2D may also be implicated in Parkinson’s disease and myotonic dystrophy.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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