Thermo Fisher Scientific Phospho-NF2 (Ser13) Polyclonal Antibody
NF2 단백질의 Ser13 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫드 반응성. 고순도 정제 및 안정적 PBS/glycerol buffer 제공. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-NF2 (Ser13) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NF2 (Accession P35240), corresponding to amino acid residues around phosphorylated Ser13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816992 |
Product Specific Information
Antibody detects endogenous levels of NF2 / Merlin only when phosphorylated at Ser13.
Target Information
NF2 encodes a protein, Merlin, that is similar to members of the ERM family, which link cytoskeletal components with cell membrane proteins. Merlin interacts with cell-surface proteins, cytoskeletal regulators, and ion transport proteins. High expression occurs during embryonic development; in adults, it is found in Schwann cells, meningeal cells, lens, and nerve. Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities. Multiple isoforms are produced via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.