Thermo Fisher Scientific CLCN7 Polyclonal Antibody
CLCN7 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western Blot, IHC, ICC/IF 등에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CLCN7 (Accession P51798), corresponding to amino acid residues M1–A40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850951 |
Product Specific Information
Antibody detects endogenous levels of total CLCN7.
Target Information
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and intracellular organelles.
This gene encodes chloride channel 7. Defects in this gene cause osteopetrosis autosomal recessive type 4 (OPTB4), also known as infantile malignant osteopetrosis type 2, and autosomal dominant osteopetrosis type 2 (OPTA2), also known as Albers-Schonberg disease or marble disease.
Osteopetrosis is a rare genetic disease characterized by abnormally dense bone due to defective resorption of immature bone. OPTA2 is the most common form, occurring in adolescence or adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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