Thermo Fisher Scientific STAC3 Monoclonal Antibody (1G8)
STAC3 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체(1G8)입니다. Western blot 및 ELISA에 적합하며, 인간 반응성을 가지는 Mouse IgM 형 항체입니다. 비결합형 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G8 |
| Immunogen | STAC3 (AAH08069, 1 a.a. ~ 325 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MELPPEPQAN GEAVGAGGGP IYYIYEEEEE EEEEEEEPPP EPPKLVNDKP HKFKDHFFKK PKFCDVCARM IVLNNKFGLR CKNCKTNIHE HCQSYVEMQR CFGKIPPGFH RAYSSPLYSN QQYACVKDLS AANRNDPVFE TLRTGVIMAN KERKKGQADK KNPVAAMMEE EPESARPEEG KPQDGNPEGD KKAEKKTPDD KHKQPGFQQS HYFVALYRFK ALEKDDLDFP PGEKITVIDD SNEEWWRGKI GEKVGFFPPN FIIRVRAGER VHRVTRSFVG NREIGQITLK KDQIVVQKGD EAGGYVKVYT GRKVGLFPTD FLEEI
Target Information
The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions.
STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 domains. It exists as two alternatively spliced isoforms and maps to human chromosome 12q13.3. Chromosome 12 encodes over 1,400 genes (≈4.5% of the human genome) and is associated with various diseases such as hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome, and trisomy 12p, which causes facial developmental defects and seizure disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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