Thermo Fisher Scientific STAC3 Monoclonal Antibody (1G8)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MELPPEPQAN GEAVGAGGGP IYYIYEEEEE EEEEEEEPPP EPPKLVNDKP HKFKDHFFKK PKFCDVCARM IVLNNKFGLR CKNCKTNIHE HCQSYVEMQR CFGKIPPGFH RAYSSPLYSN QQYACVKDLS AANRNDPVFE TLRTGVIMAN KERKKGQADK KNPVAAMMEE EPESARPEEG KPQDGNPEGD KKAEKKTPDD KHKQPGFQQS HYFVALYRFK ALEKDDLDFP PGEKITVIDD SNEEWWRGKI GEKVGFFPPN FIIRVRAGER VHRVTRSFVG NREIGQITLK KDQIVVQKGD EAGGYVKVYT GRKVGLFPTD FLEEI

Target Information

The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions.

STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 domains. It exists as two alternatively spliced isoforms and maps to human chromosome 12q13.3. Chromosome 12 encodes over 1,400 genes (≈4.5% of the human genome) and is associated with various diseases such as hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome, and trisomy 12p, which causes facial developmental defects and seizure disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.