Thermo Fisher Scientific STAC3 Monoclonal Antibody (1G8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

1G8

Immunogen

STAC3 (AAH08069, 1 a.a. approximately 325 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STAC3,uniProtId:Q96MF2-1,ncbiNodeId:9606,antigenRange:1-364,antigenLength:364,antigenImageFileName:H00246329-M02A_STAC3_Q96MF2-1_House_mouse.svg,antigenImageFileNamePDP:H00246329-M02A_STAC3_Q96MF2-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MELPPEPQAN GEAVGAGGGP IYYIYEEEEE EEEEEEEPPP EPPKLVNDKP HKFKDHFFKK PKFCDVCARM IVLNNKFGLR CKNCKTNIHE HCQSYVEMQR CFGKIPPGFH RAYSSPLYSN QQYACVKDLS AANRNDPVFE TLRTGVIMAN KERKKGQADK KNPVAAMMEE EPESARPEEG KPQDGNPEGD KKAEKKTPDD KHKQPGFQQS HYFVALYRFK ALEKDDLDFP PGEKITVIDD SNEEWWRGKI GEKVGFFPPN FIIRVRAGER VHRVTRSFVG NREIGQITLK KDQIVVQKGD EAGGYVKVYT GRKVGLFPTD FLEEI

Target Information

The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain that is organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions. STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 (Src homology 3) domains. Existing as two alternatively spliced isoforms, STAC3 maps to human chromosome 12q13.3. Human chromosome 12 encodes over 1,400 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.