Thermo Fisher Scientific STAC3 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific STAC3 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB)

Tested Dilution

• 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MTEKEVLESP KPSFPAETRQ SGLQRLKQLL RKGSTGTKEM ELPPEPQANG EAVGAGGGPI YYIYEEEEEE EEEEEEPPPE PPKLVNDKPH KFKDHFFKKP KFCDVCARMI VLNNKFGLRC KNCKTNIHEH CQSYVEMQRC FGKIPPGFHR AYSSPLYSNQ QYACVKDLSA ANRNDPVFET LRTGVIMANK ERKKGQADKK NPVAAMMEEE PESARPEEGK PQDGNPEGDK KAEKKTPDDK HKQPGFQQSH YFVALYRFKA LEKDDLDFPP GEKITVIDDS NEEWWRGKIG EKVGFFPPNF IIRVRAGERV HRVTRSFVGN REIGQITLKK DQIVVQKGDE AGGYVKVYTG RKVGLFPTDF LEEI

Target Information

The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions.
STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 domains. It exists as two alternatively spliced isoforms and maps to human chromosome 12q13.3.
Chromosome 12 encodes over 1,400 genes and comprises approximately 4.5% of the human genome. It is associated with diseases such as hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome, and trisomy 12p, which can cause facial developmental defects and seizure disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.