Thermo Fisher Scientific PTGES Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: Not specified
• Publications: View 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 5–10 µg/mL
• Publications: None listed

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  • Human, Gorilla, Gibbon, Monkey, Rabbit (100%)
  • Marmoset, Dog, Elephant, Panda, Pike (92%)
  • Bovine, Hamster, Pig, Xenopus (85%)
• For IHC(P): Use heat-induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

PTGES (Prostaglandin E Synthase) is a glutathione-dependent enzyme involved in prostaglandin E synthesis.
Its expression is induced by proinflammatory cytokine IL1B and can also be upregulated by tumor suppressor protein TP53, potentially participating in TP53-induced apoptosis.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.