Thermo Fisher Scientific CD41 Monoclonal Antibody (MEM-06), PerCP
CD41(GPIIb) 인식 단일클론 항체로 인간 혈소판 및 거핵세포 표면 단백질 검출에 적합. PerCP 형광 표지로 유세포분석(Flow Cytometry)에 최적화. 4°C 보관, 동결 금지. 연구용으로만 사용 가능.
- 카탈로그번호
- MA528563
- 판매단위
- pk
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Applications
- Flow Cytometry (Flow): 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-06 |
| Immunogen | Leukocytes, LGL-type leukemia |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745522 |
Additional Formats
- Unconjugated (MA1-19246)
- Alexa Fluor 488 (MA5-18137)
- Alexa Fluor 700 (MA5-28562)
- APC (MA1-19779)
- Biotin (MA1-19518)
- FITC (MA1-19596)
- PE (MA1-19648)
- Custom conjugation available
Product Specific Information
This antibody reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains: GPIIb alpha (120 kDa) and GPIIb beta (23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Recommended dilution: for 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) consists of two subunits (120 kDa α, 23 kDa β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor.
CD41 is involved in platelet aggregation and blood coagulation by binding to von Willebrand factor, fibrinogen, fibronectin, and vitronectin upon vessel injury.
Primarily expressed in megakaryocyte–platelet lineages and during early hematopoietic differentiation.
Associated diseases include Glanzmann Thrombasthenia and Platelet type-16 bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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