Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2714)
Thermo Fisher Scientific의 Carboxypeptidase A1/CPA1 단클론 항체는 인간 및 개 시료에 반응하며, Western blot 및 IHC에 적합합니다. 단클론 Mouse IgG1 형태로, Protein A/G 정제 후 PBS 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 1357-MSM4-P0
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPA1, 2714 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CPA1 (Carboxypeptidase A1) is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue.
It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation.
CPA1 may also inhibit zymogen activation pathways. Abnormal levels are associated with pancreatic cancer, suggesting potential involvement in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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