Thermo Fisher Scientific Carboxypeptidase A1/CPA1 (Pancreatic Cancer Marker) Monoclonal Antibody (rCPA1/8518)
Carboxypeptidase A1(CPA1) 단백질을 인식하는 췌장암 마커용 단클론 항체. Western blot 및 면역조직화학(IHC)에 적합. 사람 시료 반응성, Mouse IgG1 아이소타입. Protein A/G 정제, 4°C 보관.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rCPA1/8518 |
| Immunogen | Recombinant full-length human CPA1 protein (Carboxypeptidase A1, UniProt ID: P15085-1, 1–419 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CPA1 (Carboxypeptidase A1), also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a zinc-dependent pancreatic exopeptidase that catalyzes the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation. CPA1 activity is also implicated in zymogen inhibition, potentially regulating enzyme activation pathways. Abnormal CPA1 levels have been linked to pancreatic cancer, suggesting involvement in tumor progression or suppression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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