Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2713)
Thermo Fisher Scientific의 CPA1 단클론 항체로, 인간 및 개 시료에 반응합니다. Western blot, IHC, Peptide Array에 사용 가능하며, 단백질 소화 관련 연구에 적합합니다. 액상 형태로 제공되며, -20°C 이하에서 보관합니다.
- 카탈로그번호
- 1357-MSM3-P1ABX
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPA1, 2713 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
CPA1 (Carboxypeptidase A1) is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue.
It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation.
CPA1 may also inhibit zymogen activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting a role in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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