Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2714)
Carboxypeptidase A1(CPA1)에 특이적인 단클론 항체로 Western blot, IHC(P), Peptide Array에 사용 가능. 인간 및 개 반응성. 단백질 A/G 정제, PBS 용액 형태, 보존제 없음. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPA1, 2714 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues: Heat tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
CPA1 (Carboxypeptidase A1), also known as CPA, is a 419-amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a zinc-dependent pancreatic exopeptidase that catalyzes the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation. CPA1 is also implicated in zymogen inhibition and may influence enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting a role in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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