Thermo Fisher Scientific ICAM-3 Monoclonal Antibody (ICO-60)
인간 ICAM-3(CD50)을 인식하는 마우스 단클론 항체로 Flow Cytometry에 적합. 단백질 A로 정제된 액상형 항체이며, 1 mg/mL 농도. 연구용으로 T 세포 활성화 및 면역 반응 연구에 활용 가능.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICO-60 |
| Immunogen | Leukocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 0.2% gelatin, 0.5% saccharose |
| Contains | 0.01% sodium azide |
| Storage Conditions | 4°C short term, -80°C long term |
| RRID | AB_1072537 |
Product Specific Information
MA1-7656 detects ICAM-3 from human samples.
MA1-7656 has been successfully used in flow cytometry procedures.
The MA1-7656 immunogen is leukocytes.
Target Information
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes and serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin.
ICAM-3 mediates contact between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
It plays an essential role in initiating immune responses and interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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