Thermo Fisher Scientific Separase Monoclonal Antibody (XJ11-1B12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

XJ11-1B12

Immunogen

Maltose-binding fusion protein containing the C-terminal residues 1866-1996 of human Separase. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Separase,uniProtId:Q14674-1,ncbiNodeId:9606,antigenRange:1866-1996,antigenLength:2120,antigenImageFileName:MA1-16595_Separase_Q14674-1_House_mouse.svg,antigenImageFileNamePDP:MA1-16595_Separase_Q14674-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.9 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_568730

Product Specific Information

This Separase (XJ11-1B12) antibody is useful for Western Blot, where a band is seen at ~220 kDa (full-length form) and ~65 kDa (auto-processed form).

Target Information

Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.