Thermo Fisher Scientific RAD21 Monoclonal Antibody (CM110-2C10)
RAD21 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 및 Mouse 시료 반응성. Protein G 정제, 1 mg/mL 농도, PBS buffer 및 0.1% sodium azide 포함. -20°C 보관, 동결/해동 반복 피함.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CM110-2C10 |
| Immunogen | N-terminus fusion protein of the C-terminal fragment (residues 544–631) of the Scc1 subunit of human cohesin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568497 |
Product Specific Information
In Western blot, two bands are observed:
- Full-length Rad21 (~130 kDa)
- Cleaved Rad21 (~70 kDa)
Suggested positive control: antigen standard for RAD21 (transient overexpression lysate), HeLa whole cell extract.
Target Information
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing.
The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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