Thermo Fisher Scientific ANGPTL7 Polyclonal Antibody
ANGPTL7 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC(P) 검증 완료. 인간, 마우스, 랫트 반응성. 1 mg/mL 액상 형태, 항원 친화 크로마토그래피로 정제. 안점막 연구 및 녹내장 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 301–346 of Human Angptl7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553594 |
Product Specific Information
- Detects endogenous ANGPTL7 protein at approximately 40 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Angptl7 (angiopoietin-like 7), also known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein expressed specifically in the stromal layer of the cornea.
It forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain.
Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression.
The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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