Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 1-50 of human Cdc42EP2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDC42EP2,uniProtId:O14613-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:210,antigenImageFileName:PA5-36579_CDC42EP2_O14613-1_Rabbit.svg,antigenImageFileNamePDP:PA5-36579_CDC42EP2_O14613-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553596

Product Specific Information

This antibody detects endogenous protein at a molecular weight of 23 kDa.

Purity is >95% by SDS-PAGE.

Target Information

Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.