Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody

Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Species Reactivity

• Human
• Mouse
• Rat

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

• Synthetic peptide corresponding to amino acids 1–50 of human Cdc42EP2

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1 mg/mL

Purification

• Antigen affinity chromatography

Storage Buffer

• PBS, pH 7.2

Contains

• 0.02% sodium azide

Storage Conditions

• Store at 4°C for short term
• For long term storage, store at -20°C
• Avoid freeze/thaw cycles

Shipping Conditions

• Wet ice

RRID

• AB_2553596

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Product Specific Information

This antibody detects endogenous protein at a molecular weight of 23 kDa.
Purity is >95% by SDS-PAGE.

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Target Information

Cdc42, a small GTPase, regulates actin polymerization, elongation of cell shape, and cell signaling through interactions with various downstream effector proteins containing a CRIB domain.
Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein localized to both cytoplasm and cytoskeleton. It contains one CRIB domain and is highly expressed in heart, with lower levels in liver and pancreas.
Cdc42EP2 interacts with Cdc42 and is thought to be involved in actin cytoskeleton organization and may influence actin filament assembly and overall cell shape.

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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.