Thermo Fisher Scientific JNK1/JNK3 Recombinant Rabbit Monoclonal Antibody (JJ08-86)
JNK1/JNK3 단백질을 인식하는 재조합 토끼 단일클론 항체로, 높은 특이성과 민감도를 제공합니다. Western blot 및 Immunoprecipitation에 적합하며, HEK293 세포에서 발현되었습니다. 일관된 로트 품질과 동물 유래 성분이 없는 포뮬레이션을 제공합니다.
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Applications
- Western Blot (WB): 1:1,000–1:2,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ08-86 |
| Immunogen | Recombinant protein within Human JNK1 + JNK3 (aa 1–423) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809730 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The encoded protein belongs to the MAP kinase family, which integrates multiple biochemical signals and participates in cellular processes such as proliferation, differentiation, transcription regulation, and development.
This kinase is activated by various stimuli and mediates immediate-early gene expression. Activation by TNF-alpha is required for TNF-alpha-induced apoptosis and is also involved in UV radiation-induced apoptosis via the cytochrome c-mediated cell death pathway.
Mouse studies suggest roles in T cell proliferation, apoptosis, and differentiation. Multiple alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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