Thermo Fisher Scientific RKHD2 Polyclonal Antibody
RKHD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 적합하며 인간, 생쥐, 랫트 반응성을 가집니다. 항원 친화 크로마토그래피로 정제되었으며 PBS에 0.02% sodium azide 포함. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the carboxy terminus of human RKHD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153961 |
Product Specific Information
- A suggested positive control is rat heart tissue lysate.
- PA5-20622 can be used with blocking peptide PEP-0742.
Target Information
Rkhd2, also known as MEX3C, is a member of a novel family of four homologous human MEX3 proteins, each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.
MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and cytoplasm via the CRM1 export pathway.
These proteins are evolutionarily conserved RNA-binding proteins involved in post-transcriptional regulatory mechanisms.
Genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8.
Rkhd3 and Rkhd4, but not Rkhd2, co-localize with hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), which are centers of mRNA turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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