
Thermo Fisher Scientific Phospho-RAD17 (Ser656) Recombinant Superclonal Antibody (12HCLC)
RAD17 단백질의 Ser656 인산화 부위를 인식하는 재조합 Superclonal 항체로, 인간 시료에 반응하며 WB 및 ICC/IF에 적합. 폴리클로날의 감도와 모노클로날의 특이성을 결합한 안정적 재조합 항체. 단기 4°C, 장기 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 12HCLC |
| Immunogen | Peptide corresponding to Human RAD17 (aa 653–660) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2632996 |
Product Specific Information
This antibody is predicted to react with Monkey, Sheep, and Bovine.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies to achieve the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with consistent lot-to-lot reproducibility.
While functionally similar to polyclonal antibodies—recognizing multiple epitopes and providing high sensitivity for low-abundance targets—Superclonal antibodies have defined mixtures of light and heavy chains, eliminating biological variability in production.
Note: Formerly called “Recombinant polyclonal antibody”; now rebranded as “Recombinant Superclonal™ antibody”. Product performance remains unchanged.
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It exhibits weak ATPase activity necessary for chromatin binding and participates in recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, contributing to CHEK1 activation. Rad17 may also act as a sensor of DNA replication progression and play a role in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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